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Active Ingredients: Trazodone
Pronunciation: traz' oh done
Representative Names: Desyrel
Class: Antidepressant, miscellaneous
Generic Available? Yes
|Trazodone 50mg - 100 Tabs
|Trazodone 100mg - 100 Tabs
|Trazodone 150mg - 100 Tabs
Trazodone HCl (generic Desyrel) is a modified
cyclic antidepressant used as a treatment for
depression. It may also be used for relief of an anxiety disorder
(e.g., tension, sleeplessness),
chronic pain or to treat other conditions as determined by your doctor.
How does it work?
Trazodone blocks the ability of the nerve terminals
to bind and break down serotonin so that more is
available for the brain to use. Abnormally low levels of serotonin
may play a role in depression.
A main side effect of trazodone is drowsiness, which makes it a useful
medication to treat insomnia.
According to the Federal Law – you need a
mandatory prescription by a licensed practitioner to buy
Trazodone. In order to buy Trazodone online, you need to fill up
medical inquiry form/questionnaire.
If your prescription is approved by our registered medical practitioner,
your medication will be shipped
discreetly to your home very next day. If your prescription is not
approved, you will get full refund of
The drug information herein is intended to supplement, not substitute
for, the expertise and judgment of your physician, pharmacist or
other healthcare professional. It should not be construed to indicate
that use of the drug is safe, appropriate, or effective for you.
Consult your healthcare professional before using this drug.
Trazodone is prescribed for the treatment of depression.
How to Take
Follow the directions for using Trazodone HCl provided
by your doctor. TAKE THIS MEDICINE with food. STORE THIS MEDICINE
at room temperature in a tightly-closed container, away from heat
and light. CONTINUE TO TAKE THIS MEDICINE even if you feel better.
Do not miss any doses.
Side effects cannot be anticipated. If any develop or
change in intensity, let your doctor as soon as possible. Only your
doctor can decide if it is safe for you to keep using Trazodone Hydrochloride.
More common side effects may include:
Abdominal or stomach disorder,
constipation, aches or pains in muscles and bones, anger or hostility,
blurred vision, brief loss of consciousness, confusion, nervousness,
decreased appetite, diarrhea, dizziness or light-headedness, drowsiness,
dry mouth, excitement, fainting, fast or fluttery heartbeat, fatigue,
fluid retention and swelling, headache, inability to fall or stay
asleep, low blood pressure, nasal or sinus congestion, nausea, nightmares
or vivid dreams, tremors, uncoordinated movements, vomiting, weight
gain or loss
Less common or rare side effects may include:
anemia, bad taste in mouth, blood in the urine, chest pain, delayed
urine flow, decreased concentration, decreased sex drive, disorientation,
ejaculation problems, excess salivation, gas, general feeling of
illness, hallucinations or delusions, high blood pressure, impaired
memory, impaired speech, impotence, increased appetite, increased
sex drive, menstrual problems, more frequent urination, muscle twitches,
numbness, prolonged erections, red, tired, itchy eyes, restlessness,
ringing in the ears, shortness of breath, sweating or clammy skin,
tingling or pins and needles
If you are sensitive to or have ever had an allergic
reaction to Trazodone (generic Desyrel) or similar drugs, you should
not take this medication. Make sure your doctor is aware of any drug
reactions you have experienced. Desyrel may cause you to become drowsy
or less alert and may affect your judgment. Therefore, you should
not drive or operate dangerous machinery or participate in any hazardous
activity that requires full mental alertness until you know how this
drug affects you. Desyrel has been associated with priapism, a persistent,
painful erection of the penis. Men who experience prolonged or inappropriate
erections should stop taking this drug and consult their doctor.
Notify your doctor or dentist that you are taking this drug if you
have a medical emergency, and before you have surgery or dental treatment.
Your doctor will ask you to stop using the drug if you are going
to have elective surgery. Be careful taking this drug if you have
heart disease. Desyrel can cause irregular heartbeats.
Trazodone HCl may intensify the effects of alcohol.
Do not drink alcohol while taking this medication. If Trazodone hydrochloride
is taken with certain other drugs, the effects of either could be
decreased, increased, or altered. It is especially important to check
with your doctor before combining Trazodone with the following:
- Antidepressant drugs known as MAO inhibitors, including Nardil
- Barbiturates such as Seconal
- Central nervous system depressants such as Demerol and Halcion
- Chlorpromazine (Thorazine)
- Digoxin (Lanoxin)
- Drugs for high blood pressure such as Catapres and Wytensin
- Other antidepressants such as Prozac and Norpramin
- Phenytoin (Dilantin)
- Warfarin (Coumadin)
Any medication taken in excess can have serious consequences.
An overdose of Trazodone in combination with other drugs can be fatal.
Symptoms of a Trazodone overdose may include: Breathing failure,
drowsiness, irregular heartbeat, prolonged, painful erection, seizures,
vomiting. If you suspect an overdose, seek medical attention immediately.
IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon
as possible. If it is almost time for your next dose, skip the missed
dose and go back to your regular dosing schedule. Do not take 2 doses
STORE THIS MEDICINE at room temperature in a tightly-closed
container, away from heat and light.
Dosage should be initiated at a low level and increased gradually
noting carefully the clinical response and any evidence of intolerance.
It should be kept in mind that there may be a lag in the therapeutic
response. Increasing the dosage rapidly does not normally shorten
this latent period and may increase the incidence of side effects.
Usual adult dosage:
The recommended initial dose is 150 to 200 mg
daily, in 2 or 3 divided doses. Trazodone should be taken shortly
after a meal or light snack in order to reduce the incidence of adverse
reactions. The initial dose may be increased according to tolerance
and response by increments of 50 mg, usually up to 300 mg daily in
divided doses. In some patients, doses up to 400 mg daily and rarely
up to 600 mg daily in hospitalized patients, may be required. Occurrence
of drowsiness may require the administration of a major portion of
the daily dose at bedtime or a reduction of dosage. Once an adequate
response has been achieved, the dosage may be gradually reduced,
with adjustment depending on therapeutic response. During prolonged
maintenance therapy the dosage should be kept at the lowest effective
Use in the elderly:
If used in the elderly, doses not exceeding one-half
the recommended adult dosage should be used, with adjustments made
depending on tolerance and response.
Because safety and effectiveness in children have not been established
trazodone is not recommended in the pediatric age group.
TRAZODONE SIDE EFFECTS
Side effects from trazodone are common:
- upset stomach
- stomach pain or gas
- weakness or tiredness
- excitement or anxiety
- dry mouth
- skin more sensitive to sunlight than usual
- changes in appetite or weight
Tell your doctor if any of these symptoms are severe or do not go
- difficulty urinating
- frequent urination
- blurred vision
- changes in sex drive or ability
- excessive sweating
If you experience any of the following symptoms, call your doctor
- jaw, neck, and back muscle spasms
- slow or difficult speech
- shuffling walk
- persistent fine tremor or inability to sit still
- dizziness or lightheadedness
- blood in urine
- difficulty breathing
- shortness of breath
- severe skin rash
- yellowing of the skin or eyes
- irregular heartbeat
- prolonged or inappropriate erection
TRAZODONE CAUTIONS :
Trazodone should be used with caution in some circumstances, and
not at all in others. To ensure that your treatment is as safe and
effective as possible, inform your prescribing physician about any
history of the following conditions.
- Alcoholism or Drug Abuse : Your doctor may want to monitor
your treatment more carefully, it is not safe to use alcohol or
other drugs while undergoing trazodone treatment.
- Allergies : If you have had an allergic reaction to this
medication in the past, you should not take it. Inform your doctor
of any other food, dye, or drug allergies.
- Cardiovascular : If you have had a recent heart attack,
you should not use trazodone. If you are being treated with hypertension,
your doctor may need to adjust the doses of your medications. This
medication can make certain cardiovascular conditions worse, use
with caution, and the advice of a fully informed physician.
- Carcinoid Syndrome : Do not take this medication.
- Epilepsy or Seizure Disorder : This medication may interact
with other medications used to treat seizure disorder, speak to
your doctor about safe medication schedules or dosage adjustments.
- Kidney or Liver Dysfunction : Increased risk of side effects,
as the medication may build up in the body. Dosing adjustment may
- Pregnant or Breastfeeding : Speak to your doctor for guidelines,
absolutely avoid this medication in the first trimester of pregnancy
or if you plan to become pregnant.
- Priapism : Speak to your doctor before using this drug
if you have experienced sustained erection lasting 4 hours or more.
- Electroshock Therapy : Consult your physician if you need
this therapy while using trazodone.
- Surgery : Inform your doctor, dentist, or surgeon if you
need to have a procedure performed requiring anesthesia. Trazodone
may interact with certain drugs used in surgery, and could lead
to severe oversedation.
Overdosage of trazodone may cause an increase in incidence
or severity of any of the reported adverse reactions, e.g. hypotension
and excessive sedation. In one known suicide attempt, the patient
presented with symptoms of drowsiness and weakness 3 hours after
ingesting 7.5 g (12.5 times the maximum daily dose) of trazodone.
Recovery was uneventful. Death by deliberate or accidental overdosage
has not been reported.
There is no specific antidote for trazodone. Management
of overdosage should, therefore, be symptomatic and supportive. Any
patient suspected of having taken an overdosage should be admitted
to hospital as soon as possible and the stomach emptied by gastric
lavage. Forced diuresis may be useful in facilitating elimination
of the drug.
If overdose is suspected, contact your local poison control center
or emergency room immediately. Symptoms of overdose may include
slow, rapid or irregular pulse; unusual drowsiness or dizziness;
vomiting; weakness; loss of consciousness; and seizures.