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Active Ingredients: Trazodone
Pronunciation: traz' oh done
Representative Names: Desyrel
Class: Antidepressant, miscellaneous
Generic Available? Yes

Product Pharmacy Price Shipping Total
Trazodone 50mg - 100 Tabs Rx4US $37.47 $15.00


Trazodone 100mg - 100 Tabs Rx4US $58.00 $15.00 $73.00
Trazodone 150mg - 100 Tabs Rx4US $76.00 $15.00 $91.00

Trazodone HCl (generic Desyrel) is a modified cyclic antidepressant used as a treatment for depression. It may also be used for relief of an anxiety disorder (e.g., tension, sleeplessness), chronic pain or to treat other conditions as determined by your doctor.

How does it work?
Trazodone blocks the ability of the nerve terminals to bind and break down serotonin so that more is available for the brain to use. Abnormally low levels of serotonin may play a role in depression. A main side effect of trazodone is drowsiness, which makes it a useful medication to treat insomnia.

Important Notice
According to the Federal Law – you need a mandatory prescription by a licensed practitioner to buy Trazodone. In order to buy Trazodone online, you need to fill up medical inquiry form/questionnaire. If your prescription is approved by our registered medical practitioner, your medication will be shipped discreetly to your home very next day. If your prescription is not approved, you will get full refund of your money.

The drug information herein is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


Trazodone is prescribed for the treatment of depression.

How to Take
Follow the directions for using Trazodone HCl provided by your doctor. TAKE THIS MEDICINE with food. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. CONTINUE TO TAKE THIS MEDICINE even if you feel better. Do not miss any doses.

Side Effects
Side effects cannot be anticipated. If any develop or change in intensity, let your doctor as soon as possible. Only your doctor can decide if it is safe for you to keep using Trazodone Hydrochloride.

More common side effects may include:
Abdominal or stomach disorder, constipation, aches or pains in muscles and bones, anger or hostility, blurred vision, brief loss of consciousness, confusion, nervousness, decreased appetite, diarrhea, dizziness or light-headedness, drowsiness, dry mouth, excitement, fainting, fast or fluttery heartbeat, fatigue, fluid retention and swelling, headache, inability to fall or stay asleep, low blood pressure, nasal or sinus congestion, nausea, nightmares or vivid dreams, tremors, uncoordinated movements, vomiting, weight gain or loss

Less common or rare side effects may include:
Allergic reactions, anemia, bad taste in mouth, blood in the urine, chest pain, delayed urine flow, decreased concentration, decreased sex drive, disorientation, ejaculation problems, excess salivation, gas, general feeling of illness, hallucinations or delusions, high blood pressure, impaired memory, impaired speech, impotence, increased appetite, increased sex drive, menstrual problems, more frequent urination, muscle twitches, numbness, prolonged erections, red, tired, itchy eyes, restlessness, ringing in the ears, shortness of breath, sweating or clammy skin, tingling or pins and needles

If you are sensitive to or have ever had an allergic reaction to Trazodone (generic Desyrel) or similar drugs, you should not take this medication. Make sure your doctor is aware of any drug reactions you have experienced. Desyrel may cause you to become drowsy or less alert and may affect your judgment. Therefore, you should not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until you know how this drug affects you. Desyrel has been associated with priapism, a persistent, painful erection of the penis. Men who experience prolonged or inappropriate erections should stop taking this drug and consult their doctor. Notify your doctor or dentist that you are taking this drug if you have a medical emergency, and before you have surgery or dental treatment. Your doctor will ask you to stop using the drug if you are going to have elective surgery. Be careful taking this drug if you have heart disease. Desyrel can cause irregular heartbeats.

Drug Interactions
Trazodone HCl may intensify the effects of alcohol. Do not drink alcohol while taking this medication. If Trazodone hydrochloride is taken with certain other drugs, the effects of either could be decreased, increased, or altered. It is especially important to check with your doctor before combining Trazodone with the following:

  • Antidepressant drugs known as MAO inhibitors, including Nardil and Parnate
  • Barbiturates such as Seconal
  • Central nervous system depressants such as Demerol and Halcion
  • Chlorpromazine (Thorazine)
  • Digoxin (Lanoxin)
  • Drugs for high blood pressure such as Catapres and Wytensin
  • Other antidepressants such as Prozac and Norpramin
  • Phenytoin (Dilantin)
  • Warfarin (Coumadin)

Medical Notes
Any medication taken in excess can have serious consequences. An overdose of Trazodone in combination with other drugs can be fatal. Symptoms of a Trazodone overdose may include: Breathing failure, drowsiness, irregular heartbeat, prolonged, painful erection, seizures, vomiting. If you suspect an overdose, seek medical attention immediately.

Missed Dose
IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light.


Dosage should be initiated at a low level and increased gradually noting carefully the clinical response and any evidence of intolerance. It should be kept in mind that there may be a lag in the therapeutic response. Increasing the dosage rapidly does not normally shorten this latent period and may increase the incidence of side effects.

Usual adult dosage:
The recommended initial dose is 150 to 200 mg daily, in 2 or 3 divided doses. Trazodone should be taken shortly after a meal or light snack in order to reduce the incidence of adverse reactions. The initial dose may be increased according to tolerance and response by increments of 50 mg, usually up to 300 mg daily in divided doses. In some patients, doses up to 400 mg daily and rarely up to 600 mg daily in hospitalized patients, may be required. Occurrence of drowsiness may require the administration of a major portion of the daily dose at bedtime or a reduction of dosage. Once an adequate response has been achieved, the dosage may be gradually reduced, with adjustment depending on therapeutic response. During prolonged maintenance therapy the dosage should be kept at the lowest effective level.

Use in the elderly:
If used in the elderly, doses not exceeding one-half the recommended adult dosage should be used, with adjustments made depending on tolerance and response.

Because safety and effectiveness in children have not been established trazodone is not recommended in the pediatric age group.


Side effects from trazodone are common:

  • upset stomach
  • diarrhea
  • stomach pain or gas
  • drowsiness
  • weakness or tiredness
  • excitement or anxiety
  • insomnia
  • nightmares
  • dry mouth
  • skin more sensitive to sunlight than usual
  • changes in appetite or weight

Tell your doctor if any of these symptoms are severe or do not go away:

  • constipation
  • difficulty urinating
  • frequent urination
  • blurred vision
  • changes in sex drive or ability
  • excessive sweating

If you experience any of the following symptoms, call your doctor immediately:

  • jaw, neck, and back muscle spasms
  • slow or difficult speech
  • shuffling walk
  • persistent fine tremor or inability to sit still
  • dizziness or lightheadedness
  • blood in urine
  • fever
  • difficulty breathing
  • shortness of breath
  • severe skin rash
  • yellowing of the skin or eyes
  • irregular heartbeat
  • prolonged or inappropriate erection TRAZODONE CAUTIONS :

    Trazodone should be used with caution in some circumstances, and not at all in others. To ensure that your treatment is as safe and effective as possible, inform your prescribing physician about any history of the following conditions.

    • Alcoholism or Drug Abuse : Your doctor may want to monitor your treatment more carefully, it is not safe to use alcohol or other drugs while undergoing trazodone treatment.
    • Allergies : If you have had an allergic reaction to this medication in the past, you should not take it. Inform your doctor of any other food, dye, or drug allergies.
    • Cardiovascular : If you have had a recent heart attack, you should not use trazodone. If you are being treated with hypertension, your doctor may need to adjust the doses of your medications. This medication can make certain cardiovascular conditions worse, use with caution, and the advice of a fully informed physician.
    • Carcinoid Syndrome : Do not take this medication.
    • Epilepsy or Seizure Disorder : This medication may interact with other medications used to treat seizure disorder, speak to your doctor about safe medication schedules or dosage adjustments.
    • Kidney or Liver Dysfunction : Increased risk of side effects, as the medication may build up in the body. Dosing adjustment may be necessary.
    • Pregnant or Breastfeeding : Speak to your doctor for guidelines, absolutely avoid this medication in the first trimester of pregnancy or if you plan to become pregnant.
    • Priapism : Speak to your doctor before using this drug if you have experienced sustained erection lasting 4 hours or more.
    • Electroshock Therapy : Consult your physician if you need this therapy while using trazodone.
    • Surgery : Inform your doctor, dentist, or surgeon if you need to have a procedure performed requiring anesthesia. Trazodone may interact with certain drugs used in surgery, and could lead to severe oversedation.

      Overdosage of trazodone may cause an increase in incidence or severity of any of the reported adverse reactions, e.g. hypotension and excessive sedation. In one known suicide attempt, the patient presented with symptoms of drowsiness and weakness 3 hours after ingesting 7.5 g (12.5 times the maximum daily dose) of trazodone. Recovery was uneventful. Death by deliberate or accidental overdosage has not been reported.

      There is no specific antidote for trazodone. Management of overdosage should, therefore, be symptomatic and supportive. Any patient suspected of having taken an overdosage should be admitted to hospital as soon as possible and the stomach emptied by gastric lavage. Forced diuresis may be useful in facilitating elimination of the drug.

      If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include slow, rapid or irregular pulse; unusual drowsiness or dizziness; vomiting; weakness; loss of consciousness; and seizures.

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